Our Impact

Indiana University School of Medicine has been the site of numerous breakthroughs and key findings throughout its history as a national leader in research. 

Drunkometer/Breathalyzer 

1930s–50s

Rolla N. Harger, MD, invented the drunkometer in 1931 to help curb drinking and driving. Suspects would blow into a balloon where their breath would mix with a chemical solution. The color of the solution would indicate the subject’s blood alcohol content.

Rolla Harger, MD, with his Drunkometer.

Echocardiography

1960s

Harvey Feigenbaum, MD, the "Father of Echocardiography," pioneered the most widely used cardiac imaging technique in the world through the use of sound waves.

Dr. Feigenbaum performing an early echocardiogram.

Discovery of neurotransmitter glycine

1960s

Mori Aprison discovered the inhibitory neurotransmitter, glycine, in the 1960s. Glycine is key in the processing of motor and sensory information that permits movement, vision and audition.

First DNA bank

1970s–80s

IU established the first DNA bank in the world, which took DNA from clients' blood samples to seek out markers for illnesses or conditions.

Cure for testicular cancer

1974

Lawrence H. Einhorn, MD, developed the cure for testicular cancer through a chemotherapy treatment that included the platinum-based drug cisplatin along with two additional drugs in 1974, saving countless lives.

larry einhorn as a young man in front of patient scans

Development of Prozac (Paul Stark, Eli Lilly)

1980s

Paul Stark served as a faculty member in clinical pharmacology at IU School of Medicine and was also the leader of the clinical team at Eli Lilly that developed Prozac. The Paul and Carole Stark Neurosciences Research Institute bears his name.  

Umbilical cord transplantation

1988

Hal E. Broxmeyer, PhD, and his lab pioneered the use of cord blood to treat cancer and immune disorders. The group processed the blood used in the first cord blood transplant in Paris. Cord-blood transplants have gone on to save tens of thousands of lives in the decades since. 

the broxmeyer lab staff gathers together in 1993

First normal breast tissue bank

2007

The Komen Tissue Bank is the only repository in the world for normal breast tissue and matched serum, plasma, and DNA. Samples from the bank have helped progress breast cancer research in countless studies. 

Storniolo, Rufenbarger and Clare stand in front of biobank storage

New drug to treat X-linked hypophosphatemic rickets (Burosumab)

2018

Research from Michael Econs, MD, and Kenneth White, PhD, formed the basis of new treatments for both X-linked hypophosphatemia and autosomal dominant hypophosphatemic rickets.

Drs. Econs and White at work in the lab