Indiana University School of Medicine leads a comprehensive program in Alzheimer's disease research spanning basic, translational and clinical research, focused on optimizing clinical care for patients with Alzheimer's disease. The school, ranked No. 6 in the nation for National Institute of Aging research, received $87 million in National Institutes of Health grants to fund Alzheimer's disease research. From developing the next generation of animal models and testing potential therapeutics to working alongside clinical research participants and patients in the state's largest health system, IU School of Medicine has a rich research program and expertise widely recognized around the world.
Basic and Preclinical Science
Basic scientists research the neurobiology and molecular genetics of Alzheimer’s disease to define disease mechanisms using animal models, identify therapeutic targets, rigorously test drugs and create molecules for potential drugs.
Clinical and Translational Science
Researchers in clinical and translational science test new methods to diagnose, treat and prevent Alzheimer’s disease, and advancing this research into improved diagnosis and care for patients living with the disease.
Clinical Innovation
Researchers in clinical and translational science test new methods to diagnose, treat and prevent Alzheimer’s disease, and advancing this research into improved diagnosis and care for patients living with the disease.
Featured News
Digital screening during primary care visits may lead to earlier dementia detection, care
A trio of studies led by IU School of Medicine researchers found digital testing during primary care visits showed some promise as a tool for early identification of Alzheimer’s disease and dementia in older adults.June 03, 2025
AI Innovation Through the Lens of the 2024 Nobel Prizes
This column is the first in a 4-part series from Dr. Taeho Jo titled "AI in Medicine: From Nobel Discoveries to Clinical Frontiers".May 29, 2025
Researchers investigating how gut bacteria impacts Alzheimer’s disease progression
A team of researchers at the Indiana University School of Medicine is investigating a bacterial connection between the gut microbiome and microglia actions in Alzheimer’s disease. Growing evidence has shown that the gut can impact a person’s neurological health and potentially the progression of neurodegeneration.
May 28, 2025
At the heart of Dr. Yuan Liu's research lies a powerful approach: integrating molecular data with real-world clinical information.
May 21, 2025
Researchers from the Indiana University School of Medicine are investigating why individuals who have experienced traumatic brain injuries — whether from a single or repeated impacts — have nearly two to four times greater the risk of developing Alzheimer’s disease later in life.
May 20, 2025
IU School of Medicine's Selena Wang is trying find the answer to many complexities of the brain and Alzheimer's disease using artificial intelligence.
May 06, 2025
Indiana patients are among the first people in the country to receive new disease-modifying drugs for Alzheimer's disease, contributing to the work of IU School of Medicine researchers actively studying the long-term effects of the treatments.
April 24, 2025
Dr. Taeho Jo, a recent Research Education Component Core Scholar from the Indiana Alzheimer's Disease Research Center, is working to find out how AI can better help us find care for those with Alzheimer's Disease.
April 18, 2025
Symposium invites community, scientific leaders to better understand brain health, neurodegeneration
The IU School of Medicine will highlight its robust neuroscience research program April 13 and 14 at the inaugural Center for Neurodegenerative Disorders Symposium.
March 26, 2025